CORDIS Project
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This research explores how physical forces during development influence cell movements and tissue shape, particularly in the wing of a model organism. It aims to uncover the genetic and physical mechanisms that dictate cell alignment and remodeling in response to these forces.
During development, physical forces are generated in precise patterns and produce elegant choreography of cell movements that determine tissue shape.
The function of many tissues depends not only on their shape, but on the correct alignment of planar cell polarity within the tissue.
Remarkably, recent evidence from my lab has suggested that physical forces not only shape the wing, but also align the planar polarity of its constituent cells with the proximal distal wing axis.
The wing blade is re…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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