CORDIS Project
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This project aims to develop an advanced optical microscopy method for live-cell imaging, enabling the observation of sub-cellular processes in real-time. By utilizing multicolor 3D point-spread-function engineering, it seeks to visualize chromatin dynamics and track multiple markers within live cells at high speed and…
The sub-cellular processes that control the most critical aspects of life occur in three-dimensions (3D), and are intrinsically dynamic.
While super-resolution microscopy has revolutionized cellular imaging in recent years, our current capability to observe the dynamics of life on the nanoscale is still extremely limited, due to inherent trade-offs between spatial, temporal and spectral resolution using existing approaches.We propose to develop and demonstrate an optical microscopy methodology t…
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