CORDIS Project
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This project aims to develop a targeted multimodal treatment strategy for pediatric high-grade glioma, combining drug therapies, radiotherapy, and gene therapy. By leveraging patient-derived models, it seeks to improve treatment efficacy and provide insights for future clinical trials.
Paediatric high grade glioma (pHGG) is the most common malignant childhood brain tumour with standard-of-care inevitably resulting in therapy-resistant relapse or disease progression.
The need for new combinatorial treatments is universally acknowledged; however, modern combination therapies are sparse, include at most two modalities and have so far not been able to significantly improve the dismal prognosis of the disease.In this proposal, I conceptualize a highly targeted multimodal treatment…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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