CORDIS Project
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This study focuses on understanding the causes of male infertility due to spermatogenic failure. By utilizing a novel culture system and live imaging techniques, researchers aim to explore the dynamics of chromatin during the early stages of human spermatogonial stem cells and the mechanisms behind spermatogenic arrest…
Subfertility is of major clinical, social and economical concern in Western societies.
In approximately half of the affected couples, subfertility is due to spermatogenic failure with complete spermatogenic arrest causing azoospermia being the most extreme clinical presentation.
However, despite its clinical importance, very little is known about the etiology of spermatogenic arrest.One of the most striking features of spermatogenesis is the continuously ongoing, rapid and profound change in com…
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
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