CORDIS Project
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This research explores the connection between protein translation and organelle function in eukaryotic cells. By mapping translation processes near organelles, the project aims to uncover new insights into cellular architecture and function.
In eukaryotic cells, many proteins are produced next to the organelles where they function, demonstrating a link between translation and protein targeting.
The mechanisms of this connection are mostly unknown.
In this proposal, I bring together the fields of translation regulation and organelle biogenesis to find this out. I approach the problem with a powerful combination of functional genomics and cryogenic electron tomography (cryo-ET).
First, I want to create a quantitative map of proximal t…
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