CORDIS Project
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This project investigates how gene regulatory networks and cis-regulatory elements interact to control gene expression during embryonic development. By analyzing chromatin structures in different vertebrate models, it aims to uncover the mechanisms behind conserved gene expression patterns and their evolutionary signif…
Embryonic development requires precise spatio-temporal gene expression generating numerous cell types that build the animal body plan.
Cell-fate specification and patterning are driven by developmental genes that are often expressed in complex and conserved fashion.
Gene expression is precisely modulated by gene regulatory networks (GRNs) constructed through the integration of signalling pathways acting at cis-regulatory elements (CREs).
While signalling pathways and GRNs are evolutionary constr…
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