CORDIS Project
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This project investigates the molecular organization of the cytoplasm by combining advanced imaging techniques with studies of phase-separated cellular compartments. It focuses on stress granules and centrosomes to understand how these structures form and function in living cells.
This proposal brings together two fields in biology, namely the emerging field of phase-separated assemblies in cell biology and state-of-the-art cellular cryo-electron tomography, to advance our understanding on a fundamental, yet illusive, question: the molecular organization of the cytoplasm.
Eukaryotes organize their biochemical reactions into functionally distinct compartments.
Intriguingly, many, if not most, cellular compartments are not membrane enclosed.
Rather, they assemble dynamicall…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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