CORDIS Project
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This project aims to create advanced 3D-printed models of brain metastases that replicate the tumor environment more accurately than traditional methods. These models will facilitate the development of targeted nanomedicines to improve treatment outcomes for patients with brain metastases.
Brain metastases represent a major therapeutic challenge.
Despite significant breakthroughs in targeted therapies, survival rates of patients with brain metastases remain poor.
Nowadays, discovery, development and evaluation of new therapies are performed on human cancer cells grown in 2D on rigid plastic plates followed by in vivo testing in immunodeficient mice.
These experimental settings are lacking and constitute a fundamental hurdle for the translation of preclinical discoveries into clini…
TEL AVIV UNIVERSITY
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