CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of genome architecture in antigenic variation of the Trypanosoma brucei parasite. By using advanced genome editing techniques, it aims to reveal how DNA organization influences the expression of antigens critical for the parasite's survival.
Antigenic variation is a widely employed strategy to evade the host immune response.
It has similar functional requirements even in evolutionarily divergent pathogens.
These include the mutually exclusive expression of antigens and the periodic, nonrandom switching in the expression of different antigens during the course of an infection.
Despite decades of research the mechanisms of antigenic variation are not fully understood in any organism.The recent development of high-throughput sequencing…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
