CORDIS Project
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This project focuses on understanding gene expression during cellular differentiation by utilizing an advanced optogenetic system. It aims to control regulatory proteins with precision and map their interactions within three-dimensional chromatin structures.
The orchestration of precise gene expression patterns during differentiation and development is dependent on the cis-regulatory elements of the genome, which interact and communicate in three-dimensional (3D) chromatin structures.
It is not well understood how these interactions are formed and influence gene expression.
Our ability to identify the molecular mechanisms involved is hampered by a lack of tools that provide control over the function of regulatory proteins with high temporal precisio…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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