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3D-nanoMorph is developing a novel label-free optical nanoscopy technique to achieve high-resolution imaging of live cells. This method aims to enhance the understanding of cellular processes, particularly autophagy, without the drawbacks of traditional fluorescence methods.
Label-free optical nanoscopy, free from photobleaching and photochemical toxicity of fluorescence labels and yielding 3D morphological resolution of <50 nm, is the future of live cell imaging. 3D-nanoMorph breaks the diffraction barrier and shifts the paradigm in label-free nanoscopy, providing isotropic 3D resolution of <50 nm.
To achieve this, 3D-nanoMorph performs non-linear inverse scattering for the first time in nanoscopy and decodes scattering between sub-cellular structures (organelles).…
UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET
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