CORDIS Project
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The project aims to improve dermal substitutes by replicating the complex 3D architecture of native tissue through advanced freeze-drying techniques. This will enhance cell infiltration and survival, ultimately benefiting biomedical applications in tissue engineering.
Current dermal substitutes are suboptimal and do not mimic the physiological and pathological conditions required for in vitro biological, cancer and drug discovery studies.
Extension of a well established freeze drying approach will allow replication of the complex 3D architecture and mechanics of native tissue with consequent improved cell infiltration, survival and de novo matrix deposition.
This approach will be multi-facetted.
Initially the fabrication parameters of the freeze drying system…
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